26.10.07 Medium to high throughput single cell sequencing: A guide for different scRNAseq applications Medium and high throughput single cell RNA sequencing are two approaches to obtain single cell transcriptomic profiles. Here, we highlight the differences between medium and high throughput approaches and look at some examples that illustrate the benefits of both methodologies Read more
26.07.28 Single Cell Sequencing in Aging Research: A Practical Guide Why Single Cell Resolution Matters in Aging No individuals age in the same way. And neither do different tissues and cell types. Single cell analysis… Read more
26.07.10 scRNA-seq vs snRNA-seq: Which Should You Choose for Difficult Tissue? Not every tissue easily produces a clean single-cell suspension. Brain, heart, muscle, adipose tissue, plant tissues, and frozen tissues can be difficult or impossible to… Read more
26.03.18 Strategies for Organoid Tissue Dissociation in Single Cell Multi-Omics Strategies for Organoid Tissue Dissociation in Single Cell Multi-Omics Organoids have rapidly become a cornerstone of modern biomedical research. By recapitulating the architectural complexity and… Read more
26.03.13 The Science Behind FFPE Single Cell RNA-Seq Valuable Insights from FFPE single cell RNA sequencing Do the best data really always comes from the freshest tissue? In reality, some of the most… Read more
25.08.05 How to Isolate Nuclei for Single Cell Methods Single nucleus analysis is essential for single cell studies of hard-to-dissociate or frozen tissues, and enables multi-omics assays such as scATAC-seq. However, nuclei isolation is… Read more
25.07.30 What is Single Cell ATAC Sequencing? The basics of single cell ATAC sequencing ATAC-seq stands for Assay for Transposase-Accessible Chromatin using sequencing. It maps open chromatin regions across the genome. DNA… Read more
25.07.08 What is Bulk RNA Sequencing? The basics of bulk RNA sequencing Bulk RNA sequencing (bulk RNA-seq) is a powerful transcriptomic tool that measures gene expression across a pooled population of… Read more
25.07.08 What is Single Cell RNA Sequencing? The basics of single-cell RNA sequencing As biologists, we know biology is anything but uniform. Every tissue is a mosaic of diverse cell types, each… Read more