Single cell analysis technologies are one of the most revolutionary advancements in recent years. However, volume and complexity of the generated data pose a significant challenge. This is where machine learning, deep learning and artificial intelligence have emerged as powerful tools.
28 July is World Hepatitis Day, raising awareness and to encourage the stepping up of international efforts on preventing and treating hepatitis. This blogpost summarises a few recent research utilizing single cell RNA-seq to study the mechanism of hepatitis viral infection and pathogenesis.
Single cell differential gene expression (DGE) analysis seeks to classify two (or more) gene distributions as different, where our distributions are gene expression counts from distinct populations of cells. However, we can ask the question: are all differences between distributions equivalent?
May is Skin Cancer Awareness Month. In our new blog post we summarize the latest research in the skin cancer field utilizing single cell sequencing in order to better understand the skin cancer tumor microenvironment and the prognostic signatures of different types of skin cancers.
Medium and high throughput single cell RNA sequencing are two approaches to obtain single cell transcriptomic profiles. Here, we highlight the differences between medium and high throughput approaches and look at some examples that illustrate the benefits of both methodologies.
Labor Day, also known as International Workers' Day or May Day, is a global holiday that is celebrated on May 1st each year. The division of labor is also a fundamental phenomenon of the natural world, where different organisms and cells have specialized roles and functions.
Single cell sequencing technologies can support and accelerate the development of more precise and efficient cell and gene therapies all the way from bench to bedside. Here, we conducted an inventory of the research progress of single cell sequencing in CAR-T cell therapy for readers.
High-throughput single cell analysis lets researchers see the functions of complex biological systems. Detecting key proteins at the cell surface together with gene expression adds an additional layer of information.
World Bipolar Day is observed on March 30th every year. This day is dedicated to raising awareness about bipolar disorder, affecting approximately 46 million people worldwide. Single cell sequencing enables researchers to study the molecular mechanisms underlying bipolar disorder at a deeper level.
Why ChatGPT becomes so popular in such a short period of time? What is the technique behind this phenomenal success? Would ChatGPT be used for single cell data science as well? Let’s get a bit closer and demystify it.
In 2020, tuberculosis was estimated to be the second leading cause of death from an infectious disease after COVID-19. Here, we bring you an overview of recent studies that used single cell sequencing in order to characterize the immune response to M. tuberculosis infection in various research systems.
World Kidney Day is a global campaign to raise awareness about the importance of your kidneys. Your kidneys are an amazing, underappreciated organ! These complicated bean-shaped organs, sit either side of your spine and perform vital tasks to keep us healthy.
Researchers found that T cells, which are a type of white blood cell, could be used to target and destroy cancer cells in the same way that they target and destroy viruses and other pathogens. T cells could be collected from a person and genetically modified to express chimeric antigen receptors (CARs).
Women have made substantial contributions to science throughout history, but their accomplishments have often been overlooked or underrepresented. To revendicate the International Day of Women and Girls in Science, let´s point to some outstanding contributions of female researchers.
Single cell sequencing has the capability to transform plant research and can be applied to different fields of plant studies.
Donating blood has the potential to save lives. It can be a lifeline in emergency situations. scRNAseq has recently played a vital role in researching hematological diseases, such as leukemia, multiple myeloma, and lymphoma.
Understanding the underlying mechanisms triggering disease development and progression may allow us to identify new diagnostic biomarkers and to develop new treatment strategies. Here, we review recent studies addressing these important questions using single cell sequencing technologies.
Happy new year everyone! After the festive season full of delicious food and mulled wine in December, it’s time to slow down during Dry January!
As January is Cervical Cancer Awareness Month, we bring you here a selection of recent studies that examined cervical cancer at single cell resolution.
Here we show examples of noteworthy single-cell sequencing studies in less frequently used model organisms.
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