25.10.28 Quality controls after tissue dissociation for single cell RNA sequencing When cells come together, they form tissues and organs. These building blocks exhibit diverse cell-type-specific traits and gene expression patterns that dictate a tissue’s developmental… Read more
25.10.08 Should I Choose Single Cell Sequencing or Bulk Sequencing? Over the past decade, single cell sequencing has transformed how we study complex tissues and heterogeneous diseases. Meanwhile, bulk sequencing remains a gold standard for… Read more
25.10.06 Nobel Prize in Physiology or Medicine 2025: Tregs - The checks and balances in the immune system Celebration is in the air! Let’s look into the winners of the latest Nobel Prize in Physiology or Medicine, and their discovery: the Tregs. Who… Read more
25.08.05 How to Isolate Nuclei for Single Cell Methods Single nucleus analysis is essential for single cell studies of hard-to-dissociate or frozen tissues, and enables multi-omics assays such as scATAC-seq. However, nuclei isolation is… Read more
25.07.30 What is Single Cell ATAC Sequencing? The basics of single cell ATAC sequencing ATAC-seq stands for Assay for Transposase-Accessible Chromatin using sequencing. It maps open chromatin regions across the genome. DNA… Read more
25.07.08 What is Bulk RNA Sequencing? The basics of bulk RNA sequencing Bulk RNA sequencing (bulk RNA-seq) is a powerful transcriptomic tool that measures gene expression across a pooled population of… Read more
25.07.08 What is Single Cell RNA Sequencing? The basics of single-cell RNA sequencing As biologists, we know biology is anything but uniform. Every tissue is a mosaic of diverse cell types, each… Read more
25.06.25 What is Tissue Dissociation? Tissue Dissociation: The First Step Toward Single Cell Analysis Tissue dissociation is a crucial preparatory step in many biological and clinical research workflows, involving the… Read more
25.02.26 Optimising Sample Size and Cell Number for Single Cell Analysis When setting up a single cell analysis project, many researchers focus on sample numbers per group. However, statistical power—the ability to detect true biological differences—often… Read more