25.08.05 How to Isolate Nuclei for Single Cell Methods Single nucleus analysis is essential for single cell studies of hard-to-dissociate or frozen tissues, and enables multi-omics assays such as scATAC-seq. However, nuclei isolation is… Read more
25.07.30 What is Single Cell ATAC Sequencing? The basics of single cell ATAC sequencing ATAC-seq stands for Assay for Transposase-Accessible Chromatin using sequencing. It maps open chromatin regions across the genome. DNA… Read more
25.07.08 What is Bulk RNA Sequencing? The basics of bulk RNA sequencing Bulk RNA sequencing (bulk RNA-seq) is a powerful transcriptomic tool that measures gene expression across a pooled population of… Read more
25.07.08 What is Single Cell RNA Sequencing? The basics of single-cell RNA sequencing As biologists, we know biology is anything but uniform. Every tissue is a mosaic of diverse cell types, each… Read more
25.06.25 What is Tissue Dissociation? Tissue Dissociation: The First Step Toward Cellular Analysis Tissue dissociation is a crucial preparatory step in many biological and clinical research workflows, involving the breakdown… Read more
25.02.26 Optimising Sample Size and Cell Number for Single Cell Analysis When setting up a single cell analysis project, many researchers focus on sample numbers per group. However, statistical power—the ability to detect true biological differences—often… Read more
23.05.09 Medium to high throughput single cell sequencing: A guide for different scRNAseq applications Medium and high throughput single cell RNA sequencing are two approaches to obtain single cell transcriptomic profiles. Here, we highlight the differences between medium and high throughput approaches and look at some examples that illustrate the benefits of both methodologies Read more
23.04.03 Linking two worlds: RNA and protein at single cell resolution High-throughput single cell analysis lets researchers see the functions of complex biological systems. Detecting key proteins at the cell surface together with gene expression adds an additional layer oinformation. Read more