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How does Singleron’s SCOPE-chip technology capture individual cells for single cell RNA sequencing?

Singleron SCOPE-chip® uses a microwell-based partitioning approach. Loaded cells settle into individual microwells gently by gravity. By targeting cell occupancy of approximately 5–15% of microwells, the probability of multiple cells occupying the same well is limited.

Cell loading may be inspected under a bright field microscope.

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