The GEXSCOPE® Single Nuclei RNA Library Kit uses our microwell-based SCOPE® technology for comprehensive single nuclei sequencing analysis of biological samples.
Profit from the complete solution with robust high throughput for single nuclei sequencing of frozen samples or large / complex tissue and cells types.
Single nuclei sequencing in particularly interesting for samples that are challenging to dissociate and for frozen tissues.
Figure: Comparison between single cell sequencing and single nuclei sequencing of from mouse brain tissue with GEXSCOPE Single Cell RNA Library Kit and GEXSCOPE Single Nuclei RNA Library Kit. Population of neurons is significantly increased for the single nuclei data set.
with the SD-chip configuration
Full instruments-free workflow
PythoN: tissue dissociation NEO: single nuclei processing
The entire workflow from sample to library can be done in one workday
The kit is available with SD chips, for manual, Matrix or NEO operation and for 2, 4 or 16 RXNs (version dependent).
The product is suitable for fresh and frozen samples.
The kit covers Nuclei extraction solution, SCOPE-chips, barcoding beads and reagents necessary for chip loading, nuclei lysis, barcoding and library preparation.
The workflow takes about 8 hours.
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