Immune Therapy CeleSCOPE 2024The type 2 cytokine Fc–IL-4 revitalizes exhausted CD8+ T cells against cancer More info
CAR-T GEXSCOPE single cell 2024IL-10-expressing CAR-T cells resist dysfunction and mediate durable clearance of solid tumors and metastases More info
Myeloproliferative Neoplasms GEXSCOPE single cell 2024CXCL8/CXCR2 signaling mediates bone marrow fibrosis and represents a therapeutic target in myelofibrosis More info
Immune Therapy GEXSCOPE single cell 2024Using a pan-cancer atlas to investigate tumour associated macrophages as regulators of immunotherapy response More info
Oncology GEXSCOPE single cell 2023Single-cell RNA sequencing reveals tumor immune microenvironment in human hypopharygeal squamous cell carcinoma and lymphatic metastasis More info
Leukemia PythoN Instruments 2023Clonal architecture and single-cell transcriptome landscape in Richter’s syndrome More info
Non-Small Cell Lung Cancer (NSCLC) PythoN Instruments 2023Immune suppressive microenvironment in liver metastases contributes to organ-specific response of immunotherapy in advanced non-small cell lung cancer More info
Hepatocellular Carcinoma Matrix NEO 2023Targeting MMP9 in CTNNB1 mutant hepatocellular carcinoma restores CD8+ T cell-mediated antitumour immunity and improves anti-PD-1 efficacy More info