Can I use fixed samples, such as methanol-fixed or FFPE tissue, with Singleron kitsHome FAQ Single Cell Kits RetroSCOPE FFPE Single Nucleus Transcriptome Library Kit Can I use fixed samples, such as methanol-fixed or FFPE tissue, with Singleron kitsYes. Singleron’s RetroSCOPE® FFPE Single Nucleus Transcriptome Sequencing kit is compatible with FFPE samples. It does not depend on a panel of probes, and therefore offers unbiased discovery of the transcriptome profile. In addition, RetroSCOPE provides true whole transcriptome analysis, including both coding and non-coding RNAs. RetroSCOPE is species-agnostic, and is able to handle degraded FFPE samples with fragmented RNA.Methanol-fixed samples can be used with Singleron kits, although some optimization may be needed depending on the sample type.